Location: San Diego, CA
Job Summary
This position will be responsible for conducting research, experiments, and analysis in the field of radiochemistry. This role involves radiolabeling of diagnostic and therapeutic radioisotopes of peptides, small molecules, and/or antibodies as well as quality testing for in vitro and in vivo work. The Scientist will work in laboratory settings, collaborating with interdisciplinary teams to advance scientific knowledge and contribute to the advancement of all RayzeBio’s internal programs.
Job Responsibilities:
Essential duties and responsibilities include the following. Other duties may be assigned.
- Develop methods and conduct experiments to radiolabel peptides and small molecules using various isotopes such as Lu-177, Ac-225, Cu-64, and Ga6
- Develop and execute methods for the characterization of radiolabeled compounds, using techniques such as radio-HPLC and radio-TLC chromatography to analyze purity and stability of the radiolabeled compounds
- Conduct in vitro assays with radiolabeled compounds
- Develop methods and recipes and perform regular syntheses of radiotracers on automated synthesis devices
- Conduct in vitro assays with radiolabeled compounds
- Partner closely with the discovery research team to answer critical questions to advance programs
- Develop and maintain appropriate documentation, including protocol, reports and data analysis
- Maintain a clean and safe working environment.
Education and Experience:
- Master’s or PhD degree in radiochemistry, chemistry, nuclear chemistry or related field
- A minimum of 3 years of experience in radiochemistry field
- Demonstrated experience in radiochemistry techniques and quality control instruments such as HPLC, TLC and gamma counter
- Proper radiation safety practices during radiosynthesis, radioanalytical chemistry operations, and within the lab areas at all times.
Skills and Qualifications:
- Ability to work both collaboratively and independently in a fast-paced and cross-functional environment.
- Hands on experience working with radioactive materials and radiation instrumentation in a radiochemistry laboratory setting.
- Highly motivated and organized professional with the ability to work both with a team and independently
- Multi-disciplined scientist with ability to troubleshoot
- Excellent professional ethics, integrity, and ability to maintain confidential information
Physical Demands:
While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 60 pounds. Specific vision abilities required by this job include close vision and distance vision.
This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials.
Work Environment:
The noise level in the work environment is usually moderate.
The starting compensation for this job is a range from $114,815-$155,338 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.
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