Sr. Project Engineer

Location: Indianapolis


RayzeBio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio will operate as a standalone entity within the BMS organization, maintaining its biotech culture with the opportunity to leverage the best-in-class oncology capabilities of BMS. RayzeBio is developing innovative drugs against targets of solid tumors. The lead asset, RYZ101, is in Phase 3 testing for patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs), as well as earlier stage testing for patients with small cell lung cancer (SCLC). Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.


The Sr. Project Engineer is an integral part of bringing RayzeBio’s innovative drug products to patients in need. In this role, you will report to the Head of Engineering or other Engineering leadership as required and be responsible for leading engineering programs in support of the growth and commercialization efforts at the RayzeBio Indianapolis site. You will be responsible for various capital projects including but not limited to facility expansions, Hot Cell design, automation and system integration into a GMP environment. You will manage capital budgets and ensure the successful and timely launch of critical commercial programs. Additional responsibilities will include providing project engineering support cross-functionally at the site and providing engineering mentorship to junior engineers.

Job Responsibilities

Essential duties and responsibilities include the following. Other duties may be assigned.

  • Manage a wide range of engineering capital and facility expansion projects specific to radiopharmaceutical manufacturing.
  • Ensure capital project budgets and timelines are executed per plan.
  • Apply multiple engineering related disciplines as required, including but not limited to mechanical, electrical, and industrial engineering.
  • Manage the design and implementation of commercial production lines and various support systems.
  • Implement automation technologies as a replacement to existing manual operations.
  • Implement engineering and related business systems in alignment with BMS’s corporate objectives.
  • Coordination of external vendors, partners and service providers as required.
  • Comply with EHS and Radiation Safety programs and promote a culture of safety.
  • Review, author and/or revise technical documents (SOPs, URS’s, forms, etc.) as needed.
  • Ability to travel as required to support job role.
  • 15% of travel required

Education and Experience

  • 7+ years’ engineering experience required.Relevant pharmaceutical industry experience preferred.
  • Proven engineering project management experience.
  • BS/MS Engineering Degree required.
  • Professional Engineer license preferred.

Skills and Qualifications

  • Proven experience managing capital engineering projects and budgets.
  • Demonstrated knowledge in various engineering disciplines
  • Excellent professional ethics, integrity, and ability to maintain confidential information.
  • Strong time management and organizational skills.
  • Strong interpersonal communication skills.
  • Motivated, adaptable, and able to work under pressure.

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

Final, individual compensation will be decided based on demonstrated experience.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Employee assistance programs (EAP) and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance and supplemental health insurance. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, and sick time off. Parental, caregiver, bereavement, and military leave. Other perks like tuition reimbursement.

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